DefinitionThis section has been translated automatically.
Ester-type local anesthetic.
Half-lifeThis section has been translated automatically.
0,5–1 h
You might also be interested in
Pharmacodynamics (Effect)This section has been translated automatically.
After absorption hydrolysis by cholinesterase in p-aminobenzoic acid and 2-diethylaminoethanol (has a tissue expanding effect, therefore possibly with addition of adrenalin).
IndicationThis section has been translated automatically.
Infiltration and conduction anesthesia, local anesthesia of the eye.
Dosage and method of useThis section has been translated automatically.
0.5% for infiltration anaesthesia, 2% for block anaesthesia.
Standard concentrationThis section has been translated automatically.
2% in eye drops.
Undesirable effectsThis section has been translated automatically.
Allergic reactions (parasites). Contact sensitizations to procaine HCL are rare. In a large collective (n=2,165 persons tested) 12 (0.6%) positive epicutaneous tests were found. The DKG has tested procaine HCL in vaseline 2.0% so far. This application form is no longer available as a test substance in Germany. In this respect, a 1% concentration of procaine HCL in vaseline is now (as of 2016) recommended.
InteractionsThis section has been translated automatically.
Effectiveness of sulfonamides is reduced.
PreparationsThis section has been translated automatically.
Novocaine
LiteratureThis section has been translated automatically.
- Geier J et al (2016) News on the epicutaneous test series of the German Contact Allergy Group. Dermatology at work and in the environment 64: 70-75
Prof. Dr. med. Peter Altmeyer