Glossitis rhombica mediana K14.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Glossitis mediana rhombica; Lingua Brocq-Pautrier; Median rhomboid Glossitis; Rhomboid glossitis

History
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Brocq and Pautrier, 1914

Definition
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Harmless developmental anomaly of the tongue with a circumscribed papilla-free zone in the middle of the back of the tongue.

Occurrence/Epidemiology
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Common symptom that occurs in about 1.5% of the population. In diabetic patients, prevalences of about 6% are detected.

Etiopathogenesis
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Harmless developmental anomaly, which is interpreted as a deficient regression of the tubercle impar; but also angiomatous inhibition malformation. Superimposed infections (e.g. Candida infections) are observed or are triggering.

Manifestation
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After puberty, usually in the 2nd or 3rd decade of life. Rarely in children (more often in children with immune deficiencies, e.g. HIV infection). m:w=3:1.


Clinical features
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Usually asymptomatic, oval or rhomboid, also striped, axisymmetric, deep red, sharply defined mucosal area with a papilla-free surface in the middle third of the back of the tongue (always in front of the sulcus terminalis), centrally located. The surface of the lesion can be smoothly atrophic, but also sunken or raised like a cobblestone. Possible secondary changes: Small leukoplakic dislocations. Often colonization by Candia albicans.

Histology
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Epithelial hyperplasia, papilledema atrophy.

Differential diagnosis
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Non-specific chronic inflammation; drug reaction, fixed; tongue cancer; candidosis.

Therapy
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No therapy required.

Literature
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  1. Bae GY et al (2003) A case of median rhomboid glossitis. J Dermatol 30: 423-425
  2. Brocq L, Pautrier LM (1914) Glossite losangique médiane de la face dorsale de la langue. Ann dermatol syphilogr (Paris) 5: 1-18
  3. Ghabanchi J et al (2011) The prevalence of median rhomboid glossitis in diabetic patients: a case-control study. Iran Red Crescent Med J 13:503-506
  4. Martin HE, Howe ME (1938) Glossitis rhombica mediana. Ann Surge 107: 39-49
  5. Okunseri C et al (2003) Prevalence of oral lesions and percent CD4+ T-lymphocytes in HIV-infected children on antiretroviral therapy. AIDS Patient Care STDS 17: 5-11
  6. Pili FM et al (2014) Application of the novel method in the diagnosis and treatment of median rhomboid glossitis Candida-associated. Eur J Dent 8:129-131
  7. Ullmann W et al (1981) Glossitis rhombica mediana. dermatologist 32: 571-574
  8. Ullmann W et al (1981) Glossitis rhombica mediana. A study of 4422 dermatologic patients.
    Dermatologist 32:571-574.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020