HistoryThis section has been translated automatically.
Burton and Peye, 1977
DefinitionThis section has been translated automatically.
Rare, etiologically unexplained, chronic, non-microbially induced, non-follicular pustulosis of the scalp (and legs) with consecutive extensive scarring alopecia, affecting mainly elderly female patients. Considered a controversial entity. Important: clinical separation from folliculitis decalvans is necessary.
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EtiopathogenesisThis section has been translated automatically.
ManifestationThis section has been translated automatically.
Mostly older persons (average age: 70 years); no definite sex preference (w>m?); the disease tends to occur in actinically damaged skin.
Clinical featuresThis section has been translated automatically.
LaboratoryThis section has been translated automatically.
Bacteriological and mycological examinations of the pustule contents mostly negative (partial detection of Staphylococcus aureus, which many authors interpret as secondary infections).
HistologyThis section has been translated automatically.
Non-specific: Highly erect, non follicular bound intraepidermal to subcorneal pustules, adnexal reification, mononuclear infiltrate.
Differential diagnosisThis section has been translated automatically.
Folliculitis decalvans: follicular bound process
Primary bacterial folliculitis: follicular bound process; microbiological detection of bacteria
Psoriasis pustulosa generalisata: pustular formations always also outside the capillitium
Tinea capitis superficialis: rare in adults
Perifolliculitis capitis abscedens et suffodiens: follicularly bound process
Sterile eosinophilic pustulose (Ofuji): disseminated, very itchy and reddened papules and plaques with development of sterile (follicular) pustules. Confluence to larger foci is possible; also anular and polycyclic foci with central regression and peripheral progression may occur. Histologically eosinophilic dermatitis. Often also hematoeosinophilia.
External therapyThis section has been translated automatically.
Remove the crusts with aqueous quinolinol solution(e.g. Chinosol 1:1000). Then anti-inflammatory and drying external preparations such as glucocorticoid-containing tinctures, e.g. 0.1% triamcinolone tincture or 0.1% betamethasone tincture (e.g. Betnesol V crinale) as well as moist compresses with antiseptic additives such as potassium permanganate (light pink) or quinosol (1:1000).
Internal therapyThis section has been translated automatically.
Progression/forecastThis section has been translated automatically.
The clinical course is protracted with intermittent improvements and a tendency to scarring and consecutive alopecia (scarring alopecia of the Pseudopélade type - Wilk M et als. 2018).
LiteratureThis section has been translated automatically.
- Bieber T et al (1987) Erosive pustular dermatitis of the capillitium. dermatologist 38: 687-689
- Burton JL (1977) Case for diagnosis. Pustular dermatosis of the scalp. Br J Dermatol 97: Suppl 15: 67-69
- Boffa MJ (2003) Erosive pustular dermatosis of the scalp successfully treated with calcipotriol cream. Br J Dermatol 148: 593-595
- Di Lernia V et al (2016) Familial erosive pustular dermatosis of the scalp and legs successfully treated with ciclosporin. Clin Exp Dermatol 41:334-335.
- Ena P et al (1997) Erosive pustular dermatosis of the scalp in skin grafts: report of three cases. Dermatology 94: 80-84
- Laffitte E et al (2003) Erosive pustular dermatosis of the scalp: treatment with topical tacrolimus. Arch Dermatol 139: 712-714
- Layton AM et al (1995) Erosive pustular dermatosis of the scalp following surgery. Br J Dermatol 132: 472-473
- Pagliarello C et al (2015) Calcipotriol/betamethasone dipropionate ointment compared with tacrolimus ointment for the treatment of erosive pustular dermatosis of the scalp: a split-lesion comparison. Eur J Dermatol 25: 206-208
- Theiler M et al (2016) An Effective Therapy for Chronic Scalp Inflammation in Rapp-Hodgkin Ectodermal Dysplasia. Pediatric Dermatol 33: e84-e87.
- Wilk M et al (2018) Erosive pustular dermatosis of the scalp: re-evaluation of an underrated entity. JDDG 16: 15-20
Incoming links (3)Erosive pustular dermatitis of the capillitium; Giant cell arteritis; Triamcinolone acetonide tincture 0.1%;
Outgoing links (14)Calcipotriol; Egf receptor inhibitors; Folliculitis decalvans; Glucocorticosteroids systemic; Papel; Perifolliculitis capitis abscedens et suffodiens; Pruritus; Pustular psoriasis; Pustule; Pustulose sterile eosinophils; ... Show all
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