Dithranol

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Dithranol ointment 005/01/025/05/1 or 2% without or with salicylic acid 2% (NRF 11.51.); Ingram Paste; Ingram-Paste washable; Washable dithranol ointment 005/01/025/05/1 or 2% without or with salicylic acid 2% (NRF 11.52.)

Definition
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Indication
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Limited indication
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Pregnancy (1st trimester), lactation, pustular psoriasis and other exudative forms of psoriasis.

Standard concentration
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0.05-3% in creams, ointments or pastes (for stabilization mostly in combination with salicylic acid) in increasing concentration. Apply 1-2 times/day to the affected areas and wash off after 10-60 minutes. Increase the concentration depending on the local irritation approx. every 3 days.

Undesirable effects
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Erythema, brown discoloration of the skin, hair discoloration (in blonde or gray hair), contact dermatitis.

Contraindication
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Use on the eye or mucous membranes, hypersensitivity to the active substance.

Preparations
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Micanol, Psoralon (combination preparation with salicylic acid), Psoradexan mite/forte cream (combination preparation with urea)

Note(s)
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In intertriginous spaces apply dithranol in paste base, one concentration level lower than the rest of the Integument. The concentration of dithranol can be increased according to the skin condition.

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Last updated on: 29.10.2020