Piroctone olamine (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone monoethanolamine salt; CAS number: 68890-66-4; Piroctone Olamine; Piroctones Ethanolamine; Piroctonolamine

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Piroctone olamine is the synthetic ethanolamine salt of the pyridone derivative "Piroctone". Piroctone olamine is used as a preservative in cosmetic formulations. The substance inhibits the growth of microorganisms. Piroctone olamine dissolves in surfactants. This enables the active agent to be used in shampoos ( Preparations: Octopirox®). The substance is used in numerous dandruff shampoos.

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The framework conditions for preservatives that may be used in cosmetics are defined in the EC Cosmetics Regulation - 1223/2009 - Annex V.

Medically Piroctone olamine is used because of its fungicidal and antibacterial effects.

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  1. The Federal Office of Consumer Protection and Food Safety (BVL) Manage risks - protect consumers: https://www.bvl.bund.de/DE/03_Verbraucherprodukte/03_AntragstellerUnternehmen/02_Kosmetik/04_Inhaltsstoffe/bgs_fuerAntragsteller_kosmetik_gesetzlicheRegelung_inhaltsstoffe_node.html
  2. Pierard-Franchimont C et al (2002) Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% Piroctone olamine and 1% zinc pyrithione formulations. International Journal of Cosmetic Science24: 249-256.

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Last updated on: 29.10.2020